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16-й международный конгресс по ударно-волновой терапии.

Зальцбург, Австрия. 2013г.

P30
The Influence of SW on the Morpho-Functional State of Kidneys with Chronic Pyelonephritis

Boris Garilevich (1), Ruslan Valerievich Royuk (1), Uriy Kudriavtsev (2), Vladimir Kirpatovskiy (3)

Institution: (1) Filial (branch to) 3-rd Central military clinical hospital, (2) The 1st Moscow Medical University & Filial ( branch to) 3-rd Central military clinical hospital, (3) Scientific Research Institute of Urology Moscow, Russia

Device and Producing Company: AUVT Rumelit, electromagnetic source, Russia

Introduction:
One of the factors leading to the progression of inflammatory changes in the kidney is the microcirculation failure caused by interstitial tissue edema, microcirculatory stream vessels thrombosis, and the decreased vessel elasticity. The Shockwave Therapy (SWT) improving microcirculation should be useful in pyelonephritis patients.

Methods:
A clinical and experimental study was performed in order to prove the efficacy of SWT in chronic Pyelonephritis. We performed urethral ligation in rats and evaluated an e-coli culture into the ureter three times every 2 weeks. Shockwaves were applied every two-weeks over the infected rats' kidneys (Parameters: frequency 2 Hz, amplitude of pressure from 5 to 9 MPa, total number of pulse 500-1000-1500). The kidneys microcirculation in 35 patients with pyelonephritis was studied after the use of SWT.

Results:
We observed a decrease in the inflammatory infiltration in the form the prevalence of macrophages, and activation of the fibroblasts with reduction of the quantity in the control group after SWT. When we looked at the kidney bloodstream we found an increase in speed of the segmental arteries of 20% as well as a 10% in the arcuat arteries. The excretory functions also improved according the radioisotope survey after 5 to 7 sessions SWT.

Discussion:
The results indicate an improvement of blood flow in the kidney after SWT perhaps due to the activation of synthesis of prostaglandins leading to a decrease of intensity of the inflammatory reaction.

Conclusion:
Our results provide a basis for the expansion of another possible use of SWT in the complex treatment and rehabilitation of patients with infectious-inflammatory diseases of the kidneys.